Transgenic, Transgenic Mouse Production, ES Cells, Electroporation, Pronuclear Injection, Protocol, Transgenic, IVF, Cryopreservation, Microinjection, Gene Targeting,  Pipette, Mice, Mouse, Chimera, Chimeric, Microforge, Blastocysts, Morula, Aggrigation, Fusion, Pictures

Pronuclear InjectionChimeric MiceUniveristy of Utah

Transgenic/Gene Targeting Facility

  We are a full service Transgenic and Gene Targeting Facility located in scenic Salt Lake City, Utah.

   The facility is available to make transgenic mice using pronuclear injection and gene-targeted mice using ES cell technology and blastocyst injection.  

   A new tissue culture/electroporation lab has recently been built to complement the existing microinjection/surgery room and pathogen-free animal room that are currently housed in the Huntsman Cancer Institute.  

   The core offers technical advice regarding injection procedures, cell culture techniques, vector design and construction; and maintains the necessary mouse colonies for these basic procedures. 

   The Transgenic and Gene-targeting Facility also offers related procedures including sperm-freezing, rederivation of mouse lines, IVF, and karyotyping.

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