HSC Core Research Facilities
Small Animal MRI Imaging Facility
News
January 15th, 2010
Visen computer system is back online and IFP (infrared fluorescence protein) sequence has been allotted for in vivo tissue level gene uptake monitoring. Thus, we can now scan 3d volumes of mice with cells that express the IFP protein, similar to GFP protein studies.
Flourescence Tomography
The Visen Fluorescence Tomography system has four lasers for scanning mice ranging from 680-760 nm. This state-of –the-art system allows for use with custom Flourescence tags, especially useful for Nano-tech, pharmacological, and antibody tissue sequestration. Premade tags include markers for angiogenesis, osteogenesis, capthesin activity. Custom tags are made using a nitrogen-bond to the desired target. Additionally, the system works with the IFP (Infrared Flourescent Protein), which can be inserted into cells just like GFP. The system is custom built and currently coregisters in conjuction with the Inveon CT system.
Markers can be found at- www.visenmedical.com
July 17th, 2009
The Visen FMT 2500 is installed. Fluorescent markers can be found at http://www.visenmedical.com/products/fluorescence_agents/portfolio_overview/index.html Markers are available for angiogenesis, vascularity, and perfusion. Markers can be customized to nanoparticles and specific ligands such as antibodies. Tomography can be coregistered with CT or MRI.
July 3rd, 2009
The Siemens Inveon system is installed and is currently being validated. PET, SPECT, and/or CT is now possible. The Inveon system boasts higher resolution than our previous CT system. New analysis software also allows for much more complex CT analysis.
