HSC Core Research Facilities
Metabolimics Core Facility
Main
This facility is bridging the knowledge gap between phenotype and small metabolites. To perform this task the Core has purchased a MicroMass GCT Premier, a highly accurate time of flight mass spectrometer mated to a gas chromatograph (GC-MS). This instrument is able to analyze the small molecules involved in cellular metabolism in a qualitative fashion and is primarily used in the discovery phase of metabolomic analysis.
The Core recently purchased another GC-MS, a Thermo Trace gas chromatograph with a TSQ triple quaduple mass spectrometer serving as the detector. This instrument will be used in the quantification of metabolites that were found in the discovery phase. For metabolomic profiling of biofluids by nuclear magnetic resonance (NMR) the Core has purchased the Chenomx software suite. This software allows for the identification and quantification of common metabolites found in biofluids. The Metabolomics Core Facility focuses solely on the analysis of small metabolites. Within this mission several types of services are provided including: experimental design, sample preparation; instrumental analysis, assistance in data analysis.
